This study tests the effects of exercise in those most at risk for Alzheimer’s disease. To measure the effects of exercise on brain function, MRI is used to measure brain activation during a simple memory test consisting of famous and non-famous names. MRI is also used to measure the amount of blood flow in the brain after the exercise program, particularly in the hippocampus. This work will advance understanding of the effects of exercise on brain function in those at increased risk for AD, with the long-term goal of determining if exercise may help prevent or delay conversion to Alzheimer’s disease. 

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